RNA Interference Treatment For Hep C One Step Closer

Written on Tuesday, December 8th, 2009 at 11:45 pm by Shawn
Filed under Uncategorized.

In Chapter 14 of my book I talk about RNA Interference treatment and how it may be the quantum leap to helping people not only overcome Hepatitis C, but several other chronic viral infections. According to Phase I human clinical trials using microRNA by Santaris Pharma A/S, there has been some success inhibiting a specific slice of RNA that tells the hepatitis C uses to replicate.

In an article found on Physorg.com, there was an interesting result of the preliminary treatment performed on chimpanzees with chronic hep c. Unlike current pegylated interferon therapies, the viral levels did not rebound after the 12 week treatment. This is probably because an RNAi treatment does not allow a virus to mutate and develop resistance because the microRNA snippet is switching off the replication instructions. The other bonus is that it appears to help non-responders.

I look forward to following the progress of this therapy. Unfortunately, it still may be another 5 to 7 years out. There is always the possibility that it may never make it past Phase II trials. Of course, if successful this therapy would make my book obsolete, but I’m fine with that. My hope is that within a few years no one will have to deal with or worry about hepatitis C or other dangerous viruses like it ever again. Keep you hope alive!

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